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الموضوع: Mcq physiology

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    افتراضي Mcq physiology

    Nerve and muscle
    A- Choose the best answer:
    1- Slow axonal transport is important in:
    a- Transport of nerve impulse.
    b- Renewing the cytoplasm and regenerating the axon.
    c- Formation of myelin sheath.
    d- Neuro-muscular transmission.
    2- About cellular sheath ( sheath of Schwann):
    a- The outer layer of Schwann cells is called epi-neurium.
    b- Surrounds the axons of all neurons inside and outside the CNS.
    c- It is responsible for the color of the white matter of the spinal cord.
    d- It is essential for regeneration of the damaged verve fibers.
    3- Myelin sheath:
    a- Present in the myelinated and unmyelinated nerve fibers.
    b- Formed of lipoprotein complex and acts as electric insulator.
    c- It is formed of successive wrappings of the membrane of Schwann cells.
    d- It is the cause of decreased conduction of nerve impulse.
    4- Chronaxia:
    a- is the minimal stimulus which produce response after relatively long time.
    b- is the minimal time needed by the strong stimulus to produce response.
    c- is the time required to stimulate the nerve by a minimal stimulus.
    d- is the time required to stimulate the nerve by a stimulus which is double rheobase.
    5- During depolarization:
    a- voltage activated Na+ channels open.
    b- the membrane becomes impermeable to Na+.
    c- when the membrane potential reaches -55 m.v Na+& K+. channels open at the same time.
    d- K+ ions diffuse outside.
    6- The resting membrane potential is caused by:
    a- Diffusion of K+ ions outside the nerve fibers.
    b- Diffusion of Na+ ions inside the nerve fibers.
    c- Opening of the chemically activated ion channels.
    d- Opening of the voltage activated ion channels.
    7- To measure resting membrane potential:
    a- We use a special voltmeter or CRO.
    b- We put the two electrodes outside the nerve fiber.
    c- We stimulate the nerve by an effective stimulus.
    d- We put the two electrodes inside the nerve fiber.
    8- Repolarization:
    a- Occurs at first gradual then becomes fast.
    b- Results from closure of sodium gates and opening of potassium gates.
    c- is represented by the ascending limb of the spike.
    d- is followed by appearance of response.
    9- Continuous conduction:
    a- occurs in myelinated nerve fibers.
    b- occurs by jumping of charges from one node of Ranvier to another.
    c- is relatively slow 0.5-2.0 meter / second.
    d- occurs in the neuro-muscular junction.
    10- Saltatory conduction:
    a- occurs in unmyelinated nerve fibers.
    b- may reach up to 120 meter / second.
    c- occurs by jumping from one neuron to another.
    d- decreases gradually with distance till it disappears.
    11- In biphasic action potential:
    a- One electrode is put inside and the other is put outside the same nerve fiber.
    b- The two electrodes are put outside the nerve.
    c- Deflection occurs in one side only.
    d- Anelectrotonus occurs at the anode and catelectrotonus occurs at the cathode.
    12- In monophasic action potential :
    a- One electrode is put inside and the other is put outside the same nerve fiber.
    b- The spike is a large wave of short duration.
    c- The spike is followed by positive after potential then negative after potential.
    d- The ascending limb of the spike is due to K+ outflux.
    13- Local excitatory state is characterized by the following except:
    a- its magnitude is directly proportional with the intensity of the sub-minimal stimulus.
    b- does not obey all or non rule.
    c- can be summated.
    d- propagated without decrement.
    14- About A fibers all are true except:
    a- They have the greatest diameter.
    b- They conduct impulses with the greatest velocity (10-120 met./sec)
    c- They include somatic sensory and motor fibers.
    d- They are very sensitive to local anesthetic drugs.
    15- In all or non rule:
    a- A minimal stimulus produces a maximal response.
    b- The response in a single nerve fiber increases with increase intensity of stimulus.
    c- The nerve trunk either respond maximally or not respond at all.
    d- Minimal stimulus produces minimal response.
    16- Excitation contraction coupling involves all the following except:
    a- Release of Ca++ from troponin.
    b- Formation of cross bridges between actin and myosin.
    c- Spread of depolarization along the transverse tubules.
    d- Hydrolysis of ATP to ADP.
    17- Muscle fatigue is due to:
    a- Inability of the action potential to spread over the muscle.
    b- Failure of transmission in the motor nerve.
    c- Failure of neuro-muscular transmission.
    d- Depletion of energy stores.
    18- Anelectrotonus :
    a- is a localized area of depolarization .
    b- results from stimulation by effective galvanic current .
    c- is associated with decreased excitability .
    d- used to stimulate the nerve fibers .
    19- Nerve block is produced by:
    a- Sever cooling.
    b- Strong catelectrotonus.
    c- Decrease Ca++ ions.
    d- Increased Na+ ions .
    20- Which of the following has the lowest conduction velocity:
    a- A α fibers.
    b- A β fibers.
    c- B fibers.
    d- C fibers.
    21- The action potential of skeletal muscle:
    a- has a prolonged plateau phase.
    b- spread inward to all parts of the muscle via T tubules.
    c- is longer than the action potential in the cardiac muscle.
    d- cause re-uptake of Ca++ into the terminal cisternae.
    22- The function of tropomyosin in skeletal muscle include:
    a- binding to myosin during contraction
    b- acting as a relaxing protein at rest by covering the binding sites on actin.
    c- sliding on actin to produce shortening.
    d- releasing Ca++ after propagation of action potential.
    23- Cross bridges of sarcomere in skeletal muscle are made up of:
    a- Actin.
    b- Troponin.
    c- Tropomyosin.
    d- Myosin.
    24- Contraction of skeletal muscles:
    a- produces more work when the muscle contracts isometrically than when the muscle contracts isotonically.
    b- depends on external Ca++.
    c- decrease in magnitude with rapid repeated stimulation.
    d- does not depend on action potential.
    25- The action potential in a nerve fiber:
    a- results in a transient reversal of polarity of the membrane potential.
    b- is terminated by the influx of K+.
    c- is initiated by the efflux Na+.
    d- declines in magnitude as it moves along the nerve fiber.
    26- The motor end plate potential is produced by:
    a- opening of Na+ channels.
    b- opening of Na+ channels then opening of K+ channels.
    c- opening of Na+ and K+ channels at the same time.
    d- opening of Ca++ channels.
    27- Nerve block is produced by all the following except:
    a- local anesthetics.
    b- excessive cooling.
    c- deep pressure.
    d- strong catelectrotonus.
    28- As regard neuro-muscular transmission all are true except:
    a- it shows fatigue due to depletion of acetyl choline vesicles.
    b- occurs from nerve to muscle i.e. one way conduction.
    c- it is stimulated by succenyl choline.
    d- it is blocked by botulinum toxins.
    29- Red ( slow ) fibers are characterized by the following except:
    a- contains much blood capillaries.
    b- glycogen stores is low.
    c- contains high concentration of myoglobin.
    d- depends on anaerobic oxidation.
    30- As regard sarcomere all are true except:
    a- It is the distance between 2 Z membranes.
    b- It is shortened during contraction.
    c- The width of the I band does not change during contraction.
    d- The width of the A band does not change during contraction.
    31- As regard transverse tubules all are true except:
    a- it increases the surface area of the cell membrane.
    b- it transmits action potential to inside the fiber.
    c- it acts as a Ca++ stores.
    d- it is absent in smooth muscle fibers.





    B- True or false questions:
    1- Neuromuscular transmission is blocked by :
    a- prostigmine .
    b- increase Ca++ ions.
    c- acetylcholine .
    d- succinylcholine .
    2- A property shared by :
    a- Skeletal and cardiac muscle is their striated appearance.
    b- Cardiac and visceral smooth muscles is their spontaneous activity when denervated.
    c- All muscles is that contraction strength is related to their initial length.
    d- Cardiac and skeletal muscles obey all or non rule.
    3- Visceral smooth muscle differs from skeletal muscle in that:
    a- It contracts when stretched.
    b- It contains no actin or myosin.
    c- Its cells have unstable resting membrane potential.
    d- It is not paralyzed when its motor nerve is cut.
    4- The Sarcomere:
    a- is the distance between myosin and actin.
    b- is the distance between two Z membranes.
    c- is the contractile unite of the muscle.
    d- shorten when the muscle contracts .
    5- Excitability of nerve fibers :
    a- is increased by decreased temperature.
    b- is increased by increased Na+.
    c- decreased by decrease Ca++ ions.
    d- is completely lost by local anesthetic drugs .
    6- The energy of muscle contraction is derived from:
    a- ATP and creatin phosphate.
    b- muscle glycogen.
    c- lactic acid.
    d- ADP and cyclic AMP.
    7- Contraction of smooth muscles:
    a- is increased by increased Ca++.
    b- is decreased by cooling.
    c- is increased by excessive stretch.
    d- is decreased by hypotonic solutions.
    8- Smooth muscles:
    a- is innervated by the somatic nervous system.
    b- their denervation leads to paralysis.
    c- have double nerve supply.
    d- some fibers receive single nerve supply.
    9- As regards contraction of smooth muscle fibers:
    a- Ca++ influx is induced by activation of voltage gated Ca++ channels only.
    b- myosin phosphatase is essential for relaxation.
    c- relaxation occurs by decrease of intracellular Ca++ concentration.
    d- extra-cellular Ca++ plays an essential role.
    10- The frequency needed to produce tetanus :
    a- is increased by cooling.
    b- is decreased in red muscles.
    c- is increased fatigue.
    d- is decreased by anti-choline estrases.
    11-Depolarization:
    a- is associated with increase in membrane permeability to Na+.
    b- is terminated with closure of voltage activated Na+ channels.
    c- the membrane potential is moving away from zero potential.
    d- refers to an increase in membrane potential.
    12- Action potentials:
    a- are graded electric potentials.
    b- are produced by sub threshold stimuli.
    c- are associated with repolarization phase caused by outward movement of Cl-.
    d- are conducted over the surface of the excitable membranes.
    13- RMP of a nerve:
    a- is caused by unequal distribution of ions along both sides of the membrane.
    b- is caused by selective permeability of the membrane to the ions.
    c- Na+ - K+ pump has no role in RMP.
    d- is caused by inward movement of Na+ ions.
    14- As regard conduction of action potential in a nerve:
    a- in thick myelinated nerve fibers can reach up to 120 meter / second.
    b- can be inhibited by hyper-calcemia.
    c- can be increased by cooling.
    d- it is conducted with decrement.
    15- Pale ( fast) fiber:
    a- contains much blood capillaries.
    b- doesn't show fatigue.
    c- contains low concentration of myoglobin.
    d- depends on anaerobic oxidation.

    A- Choose the best answer:
    Key answer:
    1-b 2-d 3-b 4-d 5-a 6-a 7-a 8-b 9-c 10-b 11-b 12-b 13-d 14-d 15-a 16-a 17-d 18-c 19-a 20-d 21-b 22-b 23- d 24-c 25-a 26-c 27-d 28-c 29-d 30-c 31-c
    B- True or false questions:
    Key answer:
    1- F – F – F – T 2- T – T – T – F
    3- T –F – T - F 4- F – T – T – T
    5- F – T – F – T 6- T – T – F – F
    7- T – T – F – F 8- F – F – T – T
    9- F – T – T – T 10- F – T – F – T
    11- T – T – F – T 12- F – F – F – T
    13- T – T – F – F 14- T – T – F – F
    15- F – F – T - T


    التعديل الأخير تم بواسطة d.m.d ; 23-11-2007 الساعة 08:09 PM

  2. #2
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    افتراضي

    الموضوع منقووووووووووووووووووول
    من منتدى طب المنصوره على اللينك ده
    http://www.mansmed.com/forums/viewtopic.php?f=55&t=3156

  3. #3
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    افتراضي

    محمود

    جزاك الله خيرا فعلا

    وجعله الله في ميزان حسناتك

    مرسي قوي خالص جدا وبشدة

    بس بيتهيألي ان الكي انسر بتاعت التشوز مش مظبوطين او مش واضحين

    صح؟؟

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    افتراضي

    الف شكرررررررررررررررررررررررر
    بجد راااااائع بس اما نذاكر الاول ....

  5. #5
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    افتراضي

    tesada2oo lessa faker el 7agat de

  6. #6
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    افتراضي continuation

    Resting membrane potential of a nerve fiber

    a)include all the changes in membrane potential during the conduction of the nerve impulse

    b)is very close to the equilibrium potential of sodium

    c)is entirely a passive process

    d)is always around zero

    e)non of the above



    the resting membrane potential of a nerve

    a)is dependant on te permeability of the membrane to k being greater
    than the permeapility to Na

    b)is minimally affected by K concentration

    c)is is usually equal to the equilibrium potential for K

    D)IS MARKEDLY AFFECTED BY
    Na concentration




    Na+- k+ pump





    a)inactivation would gradually swell the cell





    b)contain its ATPase in the outer surface of the cell





    c)prevent intracellular accumulation of K+





    d)couples Na+ – K+ transport with a ratio 1:3



    تعبت من الكتابة

    لما اريح شوية هكمل

    فاصل ونواصل

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    افتراضي cont..

    Na+-K+ PUMP
    a)contributes to 70%of the resting membrane potential
    b)keeps high Na and K concentration inside the nerve fiber
    c)couples Na –K transport with aratio 1:1
    d)non of the above
    fibrinogen group
    a)includes factor 1 (fibrinogen) V VII and XIII
    b)they are activated by prothrombin
    c)they are increased through pregnancy , use of contraceptive pills and inflammation
    d)they are consumed during clotting , so they are present in serum
    فاصل ونواصل

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